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Elenco de Will & Grace
| Ator/Atriz | Personagem |
|---|---|
| Eric McCormack | Will Truman |
| Debra Messing | Grace Adler |
| Sean Hayes | Jack McFarland |
| Megan Mullally | Karen Walker |
| Janet Jackson | Janet Jackson |
| Bernadette Peters | Gin |
| Wanda Sykes | Cricket |
| Rosie O'Donnell | Bonnie |
| Sandra Bernhard | Sandra Bernhard |
| Lily Tomlin | Margot |
| Geena Davis | Janet Adler |
| Adam Goldberg | Kevin Wolchek |
| John Slattery | Sam Truman |
| Taye Diggs | James Hanson |
| Harry Connick Jr. | Leo Markus |
| Glenn Close | Fannie Lieber |
| Peter Jacobson | Paul Budnik |
| Patrick Dempsey | Matthew |
| Sharon Stone | Dr. Georgia Keller |
| Julian McMahon | Guy |
